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Sunday, May 6, 2012
Just don?t call it a Lightsaber
Fellow Star Wars fangirls/boys, we are one step closer to finally getting ourselves an actual lightsaber! ?Wicked Lasers?has given us the very first “lasersaber” (cough, lightsaber, cough). ?The saber attachment ?is compatible and fits around ?any of their Spyder-3 model lasers. ?It’s comprised of an aircraft-grade aluminum hilt and 32″ polycarbonate blade. ?When the saber [...]
Clinton says Bangladesh's parties must end discord
DHAKA, Bangladesh (AP) ? U.S. Secretary of State Hillary Rodham Clinton on Saturday urged Bangladesh's feuding political leaders to work together and end their most recent bout of discord for the good of their impoverished country.
Clinton said that weeks of strikes and protests that have paralyzed the country and killed at least five people have undermined development and scared of foreign investors. The actions stem from the disappearance of an opposition leader last month.
She appealed to Bangladeshis to respect the rule of law and called for a robust government investigation of the missing politician and allegations by the opposition of a brutal crackdown on dissent.
"Violent demonstrations ... exact a heavy toll, especially on Bangladesh's poorest and most vulnerable citizens," Clinton said. "They also send a negative signal to the international community about the investment climate here."
"We strongly urge all sides to settle differences through constructive political dialogue," Clinton told reporters at a news conference with Foreign Minister Dipu Moni.
She said that in a strong democracy, "everybody has to be rowing in the same direction because you are all in the same boat. You are going to make progress together or you are going to run into very turbulent waters."
Clinton visited the county as first lady with her daughter, Chelsea, in 1995 and later worked with New York's Bangaldeshi community as a U.S. senator. She said she felt strongly about the country's success. "This is personal for me," she said.
In recent weeks, the situation in the capital has grown increasingly tense. General strikes have brought the country to a standstill, leading to the arrest of dozens of opposition activists, and homemade bombs have exploded across the city.
"It is important that in this country ... everybody take seriously any disappearance, any violence against activists, any oppression of civil society, any intimidation of the press," said Clinton, who arrived in Bangladesh from China where she was embroiled in the case of a blind Chinese activist who had fled to the U.S. Embassy in Beijing. "That is just what is required in the 21st century if democracy (is to be) sustainable."
In advance of the visit by Clinton, the first secretary of state to stop in Dhaka since 2003, the opposition suspended protests in a goodwill gesture that reflects the importance Bangladeshis place on relations with the United States, one of their largest trading partners.
In talks with Prime Minister Sheikh Hasina, opposition leader Khaleda Zia and civic leaders, Clinton was stressing the importance of inclusive democracy and unity to improve living conditions in the country of 160 million that the U.S. sees as a potentially important voice for moderation among Muslim majority nations.
American officials said the trip was aimed at taking U.S.-Bangladesh ties to a new level by creating a new strategic dialogue and encouraging further cooperation on counterterrorism, health, environmental and educational issues.
Not everyone was pleased with the visit, though as dozens of students paraded through the campus of Dhaka University on Saturday to protest Clinton's visit, saying the U.S. cannot be a friend of Bangladesh and chanting, "Go, go Hillary."
At least 22 people, mostly politicians, have disappeared this year, according to a local human-rights group, Ain-o-Salish Kendra. Another Dhaka-based group, Odhikar, says more than 50 people have disappeared since 2010. Amnesty International and Human Rights Watch have blamed security agencies for the disappearances.
Sheikh Hasina and Khaleda Zia have been bitter rivals for decades but the latest anger over what the opposition says is political repression erupted into the streets after an opposition party leader, Elias Ali, went missing along with his driver April 17 from a street in Dhaka. His car was found later abandoned.
The opposition blamed the government and launched five days of general strikes over the past two weeks in protest. The government accused the opposition of hiding Ali to give it an excuse to create anarchy in the streets. He has still not been found.
The foreign minister said Bangladesh wanted the U.S. to eliminate its 15.3 percent tariff on Bangladesh's vital garment industry. Bangladesh exported $5.1 billion worth of goods ? mainly garments ? to the U.S. last year and imported $676 million worth in return.
Bangladeshi officials believe that dropping the duty will send exports soaring even further and boost the economy.
The countries are also expected to discuss an investment and trade framework agreement that would protect the huge investments of U.S. energy giants like Chevron and ConocoPhillips.
Chevron, one of the biggest foreign investors here, supplies half Bangladesh's natural gas needs, while ConocoPhillips is exploring for gas in the deep waters of the Bay of Bengal.
Clinton also was expected to raise the issue of Nobel Peace Laureate Muhammad Yunus' ouster from his Grameen Bank, which pioneered providing small loans to the poor. Clinton on Sunday is to meet the 71-year-old Yunus, a family friend, who the government forced out last year, saying he was well past the retirement age of 60.
Yunus' allies said the ouster was political and pointed to Hasina's anger at his 2007 effort to form a political party backed by the army when the country was under a state of emergency and Hasina was behind bars.
Clinton did not mention Yunus by name on Saturday but said she thought it was imperative that the government find a new managing director for the Grameen Bank.
Bangladesh is also seeking the repatriation of Rashed Chowdhury, who is facing a death sentence for his role in the 1975 assassination of independence leader Sheikh Mujibur Rahman, Hasina's father, during a military coup. The government says he lives in the United States, and the two nations have no extradition treaty.
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Ex-Milosevic allies front-runners in Serbia vote
Pre-election poster of Serbia's former President and Presidential candidate Boris Tadic splattered with paint, in Belgrade, Serbia, Thursday, May 3, 2012. Serbia's bid to join the European Union will be tested this weekend at a general election pitting ruling pro-European Union reformists against nationalists seeking closer ties with Russia. (AP Photo/Darko Vojinovic)
Pre-election poster of Serbia's former President and Presidential candidate Boris Tadic splattered with paint, in Belgrade, Serbia, Thursday, May 3, 2012. Serbia's bid to join the European Union will be tested this weekend at a general election pitting ruling pro-European Union reformists against nationalists seeking closer ties with Russia. (AP Photo/Darko Vojinovic)
A supporter of Pro-Western former Serbian President and presidential candidate Boris Tadic waves with Serbian flag reading: "For Boris" during a final pre-election rally in Belgrade, Serbia, Wednesday, May 2, 2012. Serbia's bid to join the European Union will be tested this weekend at a general election pitting ruling pro-European Union reformists against nationalists seeking closer ties with Russia. (AP Photo/Darko Vojinovic)
BELGRADE, Serbia (AP) ? Former ultranationalist allies of Slobodan Milosevic may return to power in Serbia, 12 years after the late Balkan strongman was ousted by pro-Western forces seeking European Union membership.
The first-round vote on Sunday for president, and votes for a 250-seat national assembly and local councils pit pro-EU democrats against nationalists who have gained in popularity with the EU's own economic troubles, which have dimmed the bloc's allure for many Serbs.
The two leading contenders are the Democratic Party of Boris Tadic ? who had been president until he resigned so the triple vote could be held together ? and Milosevic's former ally Tomislav Nikolic, whose right-wing populist Serbian Progressive Party has Russia's support, though he has lately claimed a shift toward the EU.
The eventual outcome could determine whether Serbia abides by EU-demanded economic and social reforms after being an isolated pariah nation under Milosevic in the 1990s because of his warmongering ? or turns to its traditional Slavic ally Russia instead.
It also will show whether Serbia continues to reconcile with its neighbors and wartime foes of the Balkan conflicts, including the former province of Kosovo, which declared independence in 2008.
Recent polls have suggested that the pro-EU camp slightly trails the nationalist bloc in the parliamentary race, but with the democrats having better chances of persuading smaller parties to form the next coalition government ? just as they did after the previous elections four years ago.
A presidential runoff is expected on May 20, as both Tadic and Nikolic are unlikely to get more than 50 percent of the first round vote that includes 12 candidates.
In March, Tadic led Serbia's bid to gain EU candidate status, which was conditional on the arrests of fugitive war crimes suspects Ratko Mladic and Radovan Karadzic. His government turned over the two wartime Bosnian Serb leaders to a U.N. tribunal in the Netherlands to face genocide charges for their part in the 1992-95 Bosnian war.
However, Tadic's popularity among Serbs has fallen because of the country's economic downturn. Faced with the global financial crisis, which slowed down much needed foreign investments, his government has seen massive job losses and plummeting living standards.
Nikolic has gained the support among voters for criticizing widespread social injustice and corruption, and for promising jobs, financial security and billions of dollars in foreign investments if he and his party win the elections.
Recent claims by Nikolic ? who has narrowly lost two consecutive presidential votes against Tadic ? that he has shifted from being staunchly anti-Western to pro-EU are not taken at face value by many Serbs, as well as by Western officials.
The former far-right politician, who is a self-declared "Russia lover," only a few years ago said that he would rather see Serbia become a Russian province than an EU member, and has hailed Mladic and Karadzic as "Serbian heroes."
"Of course I had to change, I've been a politician for 22 years," said Nikolic, nicknamed "Toma the Gravedigger" for running a cemetery in the 1980s. "The people of Serbia have changed," he said during the campaign.
Nikolic, who has split from the ultranationalist Serbian Radical Party, was in Milosevic's government during the violent crackdown against Kosovo Albanian separatists in 1999 that prompted NATO to bombard Serbia for 78 days until Milosevic pulled his troops out of the province.
Tadic told a campaign rally this week that "those who have shamed us" must not be allowed to govern Serbia. He said the voters have a choice to continue with "progress and development" or risk "the uncertainty."
Polls indicate Nikolic would not be able to come to power without the help of a small conservative party led by former president and prime minister Vojislav Kostunica, which is staunchly anti-EU and promises ?10 billion ($13 billion) in Russian "development loans" if Serbia turns to Moscow instead.
Tadic has had the support of the Socialists, the party founded by Milosevic in the 90's, but which has now switched to a pro-EU stance. The Socialists, who are likely to become kingmakers by placing third in the vote, have been noncommittal about which side they will support after the elections.
Milosevic died in his prison cell during his U.N. war crimes trial in 2006.
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Saturday, May 5, 2012
How Motivational Rates Can Inspire You To Perform Goals | Self ...
To aid get your self motivated to generally be your very best, it?s significant to often be real to you and also your fundamental values. Fret much more about your character than about how you appear to others. Ensure that that your actions always replicate your core values. Integrity sales opportunities to assurance which ends up in achievement.
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To receive your finances back on track, acquire a spending plan and also a prepare. Reaching your financial goals can help you in order to avoid problems later on down the road, pertaining to income and also your over-all well-being. Established a spending plan for yourself on the regular monthly basis and stay with it. After you?re cozy and might repay your whole bills, you then can figure in emergency money and ultimately ?splurge.?
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When you are facing a complicated problem within your life, do not be concerned to show into a team. ?There are numerous teams readily available which can assist with just about any battle that somebody faces. ?Teams offer a help system of like minded people. ?They increase your probable for achievement and provides you other folks who it is possible to continue being accountable to.
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Self assistance is all about checking your each day routines. A beneficial idea for endeavoring to much better your self is: make an effort to analyze a scenario from different views alternatively than centering on one particular personal perspective. Studying other peoples? motives can provide perception in your own in places you may not have in advance of.
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A terrific self assist idea would be to drive by yourself to become social even though you don?t feel like it. ?It really is common for depressed persons to isolate their selves and come to be a bit delinquent. ?This will damage your friendships. ?Even though it?d be unpleasant, forcing yourself for being social can help you fight your despair.
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Exercise will not be only for persons seeking to get rid of weight. The physical explanations for exercising are several. Training stimulates one?s body to supply all types of chemical compounds that ultimately consequence inside of a happier, calmer you. You don?t ought to be with the gym every single day; going for walks and running are merely as successful. ?Motivational quotes from successful people can really help you become successful.
Leon Edward helps people in Personal and Career Growth, leadership Development, Goal Setting, Success, Motivation, Self-Improvement, Happiness, Memory Improvement, Stress Reduction and more through his articles, blog posts and special reports . Join Leon Edwards Awesome Success Free, Get his personal success, development and growth weekly newsletter as well as success classics and tips on attracting success and wealth. Visit his Success-Leadership Library, Articles at http://www.AwesomeSuccess.org Leon Edward also helps people improve IQ, focus, memory, concentration, creativity, speed reading, public speaking , time management and reducing stress. Download his IQ Mind Brain Memory Self-Help library at his website http://www.IQMindBrainLibrary.comLeon Edward helps people improve in Leadership Development, Goal Setting, Success, Motivation, Self-Improvement, Happiness, Memory Improvement, Stress Reduction and more through his articles, blog posts and special reports . Join Leon Edwards Awesome Success Free, Get his personal development training, success and growth weekly newsletter as well as success classics and tips on attracting success and wealth. Visit his Success-Leadership Library, Articles at http://www.AwesomeSuccess.orgYou may also be interested in
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Breast Cancer: Mammograms Beat Thermography, Study Says
Breast cancer awareness is huge, and everyone recognizes that a pink ribbon is the symbol for this disease, which affects millions of women, and some men too. Mammograms have long been the best way to detect lumps and cancer for women, although some doctors recommend thermography as a substitution.
New research suggests, however, that thermography actually misses about 50 percent of cancers, and also delivers too many false positives to be accurate, according to Dr. C.M. Guilfoyle, a researcher at Bryn Mawr Hospital in Pennsylvania.
Thermography is a radiation-free screening method, which uses computer software to measure and compare thermal abnormalities in breasts. I essentially creates a breast ?map? to search for signs of developing cancer. The theory for this method of detection is that increased temperature is found in areas with increased blood flow, which could indicate a tumor.
A mammogram, on the other hand, provides an x-ray of the patient?s breast, which can be used detect lumps, or tumors. Researchers evaluated the technique for breast cancer screening using 180 women, who underwent biopsies after they had suspicious findings on other imaging exams. Guilfoyle stated that:
?I think we are still trying to determine the role of thermography as a breast cancer screening tool.?
The technology, marketed as the No Touch Breast Scan, was not able to tell the difference between malignant and benign lesions in most cases. The technology is still evolving, however, and it does have room to improve, given Guilfoyle?s study.
Dr. Kimberly Lovett, an attending physician at Southern California Permanente, and an investigator at the University of California-San Diego Center for Patient Safety, writes about the dangers of online ads by thermography companies, telling people that it is a good substitute, and can be the sole method for detecting breast cancer. Lovett says that:
?I would tell women that thermography continues to be studied, and the technology will hopefully improve over time. However, at this time, thermography should absolutely not be used as an alternative to screening mammogram or as an alternative to breast biopsy in the presence of a positive mammogram.?
Until a thermography method is developed that yields better results, Guilfoyle recommends sticking with a yearly mammogram for breast cancer detection.
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Antidote For Cocaine Overdose Shows Promise
Reporting in the journal Molecular Pharmaceutics, researchers write that they've developed a antidote that reverses dangerous symptoms of a cocaine overdose in mice. Study co-author Kim Janda discusses how the vaccine, made from artificially produced human antibodies against cocaine, works.
Copyright ? 2012 National Public Radio?. For personal, noncommercial use only. See Terms of Use. For other uses, prior permission required.
IRA FLATOW, HOST:
This is SCIENCE FRIDAY. I'm Ira Flatow. Stroke, kidney failure, seizures are some of the devastating effects of a cocaine overdose that kill thousands of people each year. But new research has created hope that a cocaine overdose antidote may soon be available for doctors who administer in emergency situations.
In a study published in the American Chemical Society journal Molecular Pharmaceuticals, researchers say they have developed an injectable solution that reverses the effects of a lethal dose of cocaine, at least it does so now in mice.
Dr. Kim Janda was a co-author of the study and has worked on vaccines for heroin, meth and even nicotine. He's professor in the Department of Chemistry, Immunology and Microbial Science at the Scripps Research Institute in La Jolla, and he joins us from there. Welcome to SCIENCE FRIDAY. Hello, Dr. Janda, are you there? Having trouble hearing? Dr. Janda, can you hear us?
DR. KIM JANDA: Hello?
FLATOW: Hello there.
JANDA: I can't hear the show, but I can hear you.
(SOUNDBITE OF LAUGHTER)
FLATOW: All right, we're going to have to work out our technical difficulties. Maybe we can push a button and make something happen so that Dr. Janda can hear us.
JANDA: Or just press go.
FLATOW: Or press go.
(SOUNDBITE OF LAUGHTER)
FLATOW: Dr. Janda, can you hear us?
JANDA: Yeah, I can hear you now.
FLATOW: OK, that's better. I love live radio. Thanks for taking time to be with us today. Tell us about this vaccine. This is a potential antidote. Are you saying that in mice, when the mice had a cocaine overdose, you were able to reverse the effects of it?
JANDA: Yes, that's correct. Basically when they given a lethal dose, we were able to use a pre-formed antibody and inject it, and basically the mice didn't die from the overdose, they all lived.
FLATOW: What was working there? How does it work?
JANDA: Basically it seeks out cocaine very quickly, sequesters it and removes it from the body.
FLATOW: And is this the same kind of thing that might be possible in humans?
JANDA: Well, that's what we're working towards. The antibody that we've prepared is what's known as a human monoclonal antibody versus a mouse monoclonal antibody. So we were gearing everything towards trying to move into clinical trials.
FLATOW: And so what are the next steps here?
JANDA: The next steps would be able to make it efficiently in large quantity and then test it out in some type of human trial.
FLATOW: Is it possible you might be able to create a vaccine that's used beforehand?
JANDA: Well, we and other groups have looked at what's called an active vaccine for treating cocaine addiction, but the differences between that and what we're using with what's called a passive vaccine for overdose is that the active vaccines take weeks to get onboard, and they never reach what's called an antibody titer that would be high enough to protect from a cocaine overdose.
So this is in the same genre but a little bit different venue, how we're setting this up.
FLATOW: You have been looking at vaccines for addiction, have you not?
JANDA: Sure.
FLATOW: Tell us about that search and what the difficulties are in that.
JANDA: Well, we've been looking at vaccines for cocaine, heroin, methamphetamine, nicotine addiction for well over 25 years, and while many years ago we used to think treating one addiction, one drug addiction is similar to treating another, it's not, and so we found the path to be quite difficult at times, depending on the particular drug we're working with.
FLATOW: So they all have different pathways of working, and that...
JANDA: Well, they all have different - they work differently, you know, in terms of the receptors they hit, in terms of how they're metabolized in our body and how they interact with our body's tissue. So each one is a very different animal in trying to attack.
FLATOW: Is this something that a drug company would be interested in developing, if you found some research or did some of the basic research?
JANDA: I really wish it would, but I think a lot of big drug companies don't feel that drug addicts are a great investment. So they've kind of shied away from looking at therapies for addiction. I wish they would get more involved, that's for sure.
FLATOW: Well, what about something for an overdose? You don't have to be a drug addict to have an overdose.
JANDA: That's for sure. And what we really think this overdose, if it would be moved forward with a company, would be packaged as a shot to have on - hands on, you know, with an ambulance or ER clinics for, you know, life or death situations.
FLATOW: Doesn't it raise some ethical concerns about having an antidote?
JANDA: I don't think an antidote raises the ethical concerns. The ethical concerns would be more raised with what's known as the active vaccine, which basically requires multiple injections, and you have circulating antibodies for life in that potential individual.
So, you know, one could be potentially marked that you had that vaccine. The antidote vaccine we're developing now would be eliminated in the body within a matter of days.
FLATOW: So it is possible you could create sort of a prophylactic vaccine?
JANDA: It's possible, but for the active vaccines, yeah, that's correct.
FLATOW: Is there a lot of research that's going on in this field?
JANDA: There is. It's sparse. There are some groups that have been working in this for a number of years, but like I said, it's - the research requires a lot of different initiatives. So it's not something that a group who's just doing chemistry or immunology can do. You have to kind of meld together chemistry, immunology and neuropharmacology to kind of look at this overall process.
FLATOW: And is there great interest? You say there might be interest if you can develop this in - for people, the drug companies, because it's given later, might be interested in it as opposed to giving, as you say, prophylactics to drug addicts.
JANDA: Well, I think both are quite appealing. I think for, you know, an immediate situation, the antidote is obviously much more appealing, but, you know, in terms of long-term maintenance and abstinence for possibly treating cocaine addicts, I think the active vaccine would be the best way to go.
FLATOW: What about other habit-forming drugs or dangerous drugs? Does this open the pathway for antidotes for them also?
JANDA: Sure, I think one can look at this for heroin and other drugs like that, maybe methamphetamine. I think that looking at this overall methodology, would be useful for those types of drugs also, even possibly things like Oxycodone.
FLATOW: Oxycodone, yeah, that - you say you could possibly do it with that.
JANDA: I see no reason why not.
FLATOW: And as far as human clinical trials, when might they start?
JANDA: Well, I think if we can, like I said, make it more efficiently in large quantities, then hopefully we can see someone step up to the plate who would want to partner with us and move this forward.
FLATOW: Well, good luck to you, and thank you very much for taking time to be with us.
JANDA: OK, thank you for having me on.
FLATOW: Dr. Kim Janda is the co-author of the study in the American Chemical Society journal Molecular Pharmaceuticals about a potential treatment for overdoses of cocaine and who knows what other kinds of drugs. He's a professor at the Departments of Chemistry, Immunology and Microbial Science at the Scripps Research Institute.
Copyright ? 2012 National Public Radio?. All rights reserved. No quotes from the materials contained herein may be used in any media without attribution to National Public Radio. This transcript is provided for personal, noncommercial use only, pursuant to our Terms of Use. Any other use requires NPR's prior permission. Visit our permissions page for further information.
NPR transcripts are created on a rush deadline by a contractor for NPR, and accuracy and availability may vary. This text may not be in its final form and may be updated or revised in the future. Please be aware that the authoritative record of NPR's programming is the audio.
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